March 23rd, 2016
Today we have an onslaught of negative reports on the use of medication to treat chronic pain. These specious attacks have affected every area of pain medicine in an extremely negative manner causing more and more pain for those who suffer, even those who don't require medication. Lost in all the condemnations, proclamations and recommendations about pain treatment is a most basic scientific fact about pain. Its first and foremost impact, other than agony, is its dramatic, aggressive assault on…
March 22nd, 2016
According to a comprehensive Cochrane review, opioid analgesics effectively relieve chronic noncancer pain in most patients, with only a small (though not zero) risk of developing abuse or addiction. However, it must be appreciated that a portion of patients may have inadequate pain relief or develop intolerable side effects; care must be taken to identify patients who will benefit most. Over the past few years there has been an ongoing move to villify opioids in the management of pain, which leaves…
March 2nd, 2016
Hiroshima University researchers have identified a specific molecule that maintains pain after a nerve injury and have been able to block it in lab animals. This discovery may reveal a promising therapeutic strategy for treating neuropathic pain. Lab animals with an injury to their sciatic nerve showed less pain after multiple injections of a medication that blocks the activity of a molecule called high-mobility group box-1 (HMGB1). The team also discovered that a single dose of a substance to block…
February 26th, 2016
A new group of medications being developed to treat mood disorders could also relieve chronic pain a new study from University College London (UCL) reports. The research was funded by the Medical Research Council in the United Kingdom. This study, published in Science Translational Medicine, reveals how a protein that shapes the body's response to stress also drives chronic pain and so offers new targets for future pain treatments. The researchers studied genetically modified lab…
February 25th, 2016
It is with great sadness that we learned of the passing of Dr. Levitt, who dedicated a large part of his life to provide a better understanding of pain management practices and all the myths swirling around this complex disease of pain. His experience and sheer ability to put things in perspective is and will be sorely missed.
Our sincere condolences go out to his wife and family.