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HOW THE WAR ON DRUGS IS HURTING PAIN PATIENTS

When 58-year-old ZyP Cyk has a serious mountain biking accident she refused to go to the emergency ward evrn though her injuries knocked her out cold and her husband pleaded her to seek help. Instead, Cyk slept for two days--contrary to the conventional wisdom of what you're supposed to d after sustaining a head injury and being unconscious. Only the did she finally agree to go to an urget care center, where she discovered she had broken her collarbone and some ribs and needed surgery. Cyk wasn't…
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CANADIAN STUDY DISTORTS Rx-OPIOID-RELATED DEATHS

Repeated reports of increasing deaths associated with prescribed opioid analgesic should concern us all, but they may also portray a distorted picture of the scope and urgency of the problem. This is evident in a report on mortality trends in Canada, which serves as a lesson in why readers must be wary of how such data are presented in the literature and the press. Canadian investigators supported by the Institute for Clinical Evaluative Sciences (ICES) and the Ontario Ministry of Health and Long…
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A REAL NEED FOR PAIN MANAGEMENT

Today we have an onslaught of negative reports on the use of medication to treat chronic pain. These specious attacks have affected every area of pain medicine in an extremely negative manner causing more and more pain for those who suffer, even those who don't require medication. Lost in all the condemnations, proclamations and recommendations about pain treatment is a most basic scientific fact about pain. Its first and foremost impact, other than agony, is its dramatic, aggressive assault on…
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OPIOIDS RELIEVE PAIN WITH LITTLE ADDICTION RISK

According to a comprehensive Cochrane review, opioid analgesics effectively relieve chronic noncancer pain in most patients, with only a small (though not zero) risk of developing abuse or addiction. However, it must be appreciated that a portion of patients may have inadequate pain relief or develop intolerable side effects; care must be taken to identify patients who will benefit most. Over the past few years there has been an ongoing move to villify opioids in the management of pain, which leaves…
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NEW TARGET FOR REDUCING NERVE PAIN IDENTIFIED

Hiroshima University researchers have identified a specific molecule that maintains pain after a nerve injury and have been able to block it in lab animals. This discovery may reveal a promising therapeutic strategy for treating neuropathic pain. Lab animals with an injury to their sciatic nerve showed less pain after multiple injections of a medication that blocks the activity of a molecule called high-mobility group box-1 (HMGB1). The team also discovered that a single dose of a substance to block…
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